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Potential problems include skin irritation, wasted money, and putting off proper treatment

As of early 2026, multiple Phase 3 trials have reported positive topline results, regulatory submissions have been filed, and the FDA is reviewing orforglipron for an obesity indication with a target action date of April 10, 2026

Existing Medicare Part D coverage for another approved indication may affect eligibility

A solid skincare regimen that includes clinically-proven ingredients like retinol, hyaluronic acid, and vitamin C will be helpful in combating dullness and sagging skin, too

Take Advantage of Trials : The 21-day trial for the Weight Loss Pill Program ($29) or the Noom Weight 14-day free trial can help you test the program at a lower cost

Wegovy carries the regulatory and evidence advantage