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This treatment approach of considering cardiorenal protection even in early disease stages had already been proposed by the American College of Cardiology in 2019 and has since been included in new updates of various Spanish consensus documents [10,11,12]

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In conclusion, our findings suggest that GLP-1RAs may exert neuroprotective effects by delaying IOP elevation and preventing OHT-induced reactive astrocyte and vascular remodeling

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