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The risk calculus changes accordingly
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Semaglutide - Video Overview The SURPASS-2 trial compared three doses of tirzepatide (5 mg, 10 mg, 15 mg) with semaglutide 1 mg, in adults with type 2 diabetes who were already taking metformin

Those taking semaglutide often have other health conditions that can raise the risk of NAION

Miyawaki K, Yamada Y, Ban N, et al
