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When treatment is stopped, weight regain commonly occurs, with patients typically regaining approximately two-thirds of lost weight within one year of discontinuation

Safety Monitoring and Adverse Event Profile As expected for a GLP-1 agonist, the most common side effects are gastrointestinal, including sickness, diarrhea, and vomiting

This section surveys non-oral administration routes that may be appropriate for systemically acting peptides and proteins, applying the same pharmacokinetic constraints emphasized throughout this review

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