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Patients are finally experiencing meaningful appetite control and, in many cases, significant weight loss

Expert perspectives Reacting to the readout, endocrinologist Daniel J

Clinical evidence shows no direct link, but indirect factors like dehydration and electrolytes play a role.

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However, although modern glucagon-like peptide-1 receptor agonists and related medications are highly effective for weight loss and glycaemic improvement, and generally safe, many people do not want to take drugs indefinitely, and their cost means that they are not available across much of the world