gip glp 1 dual agonist GIPR/GLP-1R therapies for diabetes and weight loss—chemistry, physiology, and clinical applications Dual GIP/GLP-1 receptor agonists: New

Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man

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Citation: Rehan Haider, Shabana N

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The groups around Jens Holst (Copenhagen, Denmark) [1] and Joel Habener (Boston, MA, USA) [2] were the first to correctly identify truncated GLP-1 (GLP-1 [736 amide], the amidated form [1], or GLP-1 [[7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37]], the glycine-extended form [2]), as the product(s) of proglucagon translational processing in mammalian gut mucosa (L cells) as published in 1987