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Furthermore, in the real-world studies reviewed, no cases of thyroid cancer, including medullary thyroid carcinoma, were observed [132]
( 10.1016/S0140-6736(2100213-0) [DOI] [PubMed] [Google Scholar] de Souza AH Tang J Yadev AK Saghafi ST Kibbe CR Linnemann AK Merrins MJ & Davis DB
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Treatment discontinuation because of adverse events occurred in 2% to 5% of retatrutide participants and 0% of placebo participants
June 2024: Structure Therapeutics reported positive Phase IIa obesity data for GSBR-1290, an oral non-peptide small-molecule GLP-1 receptor agonist, achieving 6.2% placebo-adjusted mean weight loss at 12 weeks
