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Heart and kidney protection While clinical trials have yet to study the long-term benefits of Soliqua and Xultophy, research suggests that GLP-1s on their own can help protect the heart and kidneys

That said, the SELECT trial suggests the benefits of starting GLP-1 RAs begin early, even at introductory doses

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However, their popularity has placed unprecedented financial strain on employer-sponsored health plans

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To conclude, the food intake reducing effects of exenatide may temporally evolve from strong anorectic to weak anhedonic modulations, where hedonic experience and anticipation during the early anorectic phase is conserved but uncoupled from food intake behaviour