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Erectile and endothelial dysfunction in type II diabetes: A possible link

9 The effect of metformin on fasting plasma glucose and HbA1c is dose dependent
It demonstrated that GLP-1 RAs can modulate intestinal farnesoid X receptor (FXR) signaling to improve joint health [168]
This has led to their licensed use for weight management in individuals with obesity or those who are overweight with weight-related comorbidities

2020;192(31):E875-E891

Combining both treatments can improve outcomes, though managing side effects remains critical
