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Across phase III trials of GLP-1 receptor agonist and multi-hormone receptor modulator obesity drugs in adults with overweight or obesity, the magnitude of blood pressure-lowering was closely associated with the degree of weight loss, highlighting the clinically relevant yet often underappreciated blood pressure-lowering potential of these drugs, the authors concluded

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As a result, existing players in the GLP-1 market find it increasingly challenging to sustain their market positions amidst growing affordability from generics

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Some early studies suggest GLP-1 drugs may help reduce cravings for substances like alcohol and nicotine