glp-1 updates Safety Check $50 GLP-1s? Medicare Update: Everything

Clostridium butyricum produces the postbiotic butyrate which stimulates GLP-1. Bifidobacterium infantis produces the postbiotics acetate and lactate which feed bacteria such as Akkermansia and Butyricum, promoting an ecosystem in the gut that supports a healthy gut lining and naturally boosts GLP-1

These findings are encouraging, and must be interpreted cautiously, as many studies cannot separate direct pharmacologic effects from improvements in metabolic health that accompany treatment

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32 Shor et al used a nationwide Canadian EHR database to compare 46,334 patients taking GLP-1 RAs with 92,668 controls over a follow-up period of 6 months to 3 years

Association between dipeptidyl peptidase-4 inhibitor drugs and risk of acute pancreatitis: a meta-analysis

GLP-1: GLP-1(7-36) & GLP(9-36) GLP-1 is an endocrine peptide hormone synthesized in multiple locations including: 1) L-cells located in the intestinal mucosa, 2) -cells found in the pancreatic islet, and 3) central neurons residing in the nucleus of the solitary tract, a region regulating appetite and digestion (D'Alessio, 2016)