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Although SGLT2i users generally showed a slightly reduced risk of PsA across different levels of renal function, the differences did not reach statistical significance

Geisler CE, Antonellis MP, Trumbauer W, Martin JA, Coskun T, Samms RJ, et al

SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in caenorhabditis elegans

Factors such as recent illness, ongoing side effects, or significant changes in weight or diet can influence eligibility, even if the medication itself is not a direct concern