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Mechanistically, E4s primary effect was to alleviate inflammatory responses and vascular abnormalities, with relatively modest inhibitory effects on VEGF [62]

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162 ER stress plays a complex role in the control of neuronal survival, amyloid cascade, neurodegeneration, and synaptic function in AD

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( 10.1210/endo.141.3.7366) [DOI] [PubMed] [Google Scholar] Borlaug BA Jensen MD Kitzman DW Lam CSP Obokata M & Rider OJ