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On a broader scale, Canada seems to typically prefer switches to next-generation innovative biologics over a biosimilar/generic of an older agent

The single study showing decreased b12 levels involved a specific high-risk population

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It has been reported that the annual urinary tract infection rates of upper motor neuron intestinal syndrome group and lower motor neuron intestinal syndrome group were 3.0 1.8 and 2.6 1.8, respectively (Gungor et al., 2016)
