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Am J Ophthalmol 2024;265:39-47

Most enhancement peptides have little or no human trial data, so their effects and safety in otherwise healthy people are largely unknown
Pathophysiology of HFpEF HFpEF is a multifactorial syndrome that differs fundamentally from HFrEF in its underlying pathophysiology

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When used with insulin or sulfonylureas, these medications may increase hypoglycemia risk, requiring dose adjustments of those agents
These body composition effects give new optimism for impactful obesity prevention and metabolic health
