tirzepatide lancet Incidence of new onset type 2 diabetes in adults living with obesity treated with or semaglutide: real world evidence from an international retrospective cohort study Menopause Hormone Therapy May Boost

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Further studies are now needed to investigate the mechanisms underlying treatment response and to determine whether efficacy differs between patients with suboptimal initial weight loss and those who subsequently experience weight regain, they added

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In this work we review current evidence and argue that combination therapy should be primarily deployed for high-risk patients to maximise cardiorenal benefits, provided cost and access barriers are addressed

Details of ongoing trials can be found on ClinicalTrials.gov and the EU Clinical Trials Register

doi: 10.1007/s12272-016-0875-9