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This was thought related to the rapid glucose lowering in patients with pre-existing diabetic retinopathy (a known phenomenon where quick improvement of blood sugar can transiently worsen retinopathy)

Ethical considerations are paramount, as children are a vulnerable group, requiring careful assessment of the riskbenefit ratios before exposing them to pharmacologic agents intended for weight management

Lixisenatide is administered once daily 1 hour before the first meal of the day

As these drugs are being used by an increasing group of fertile women, it is expected that a few of them will get pregnant and data on the safety of continuation would prove valuable

9-11 This review should be concluded with the acknowledgement of an important limitationthese trials had a relatively short duration