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Despite lots of big lingering questions, many clinicians dont think it actually matters right now how GLP-1 interacts with brain receptors on a cellular level, says Laura Huckins, PhD, an associate professor of psychiatry at the Yale School of Medicine

While there has been extensive research on dietary patterns and weight loss, the most effective intervention is reduction in caloric intake [19]

In a small RCT, intranasal insulin was also associated with improved cognitive function and Unified Parkinsons Disease Rating Scale (UPDRS) score [26]

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Identifying the Strong Response Endotype For the study, researchers conducted a secondary analysis of data from a previous clinical trial of tirzepatide in patients with OSA and obesity

doi: 10.1111/dom.14947 [DOI] [PubMed] [Google Scholar] 15
