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If your vial has been out for more than a few hours, check the solution for cloudiness or particles before using it
Lastly, the high proportion of female participants evaluated in this study is reflective of the natural history of type 2 diabetes in youth [40] and our study results may not be generalisable to males, although there is no evidence to suggest that there are sex differences in glucose production or response to metformin therapy [41]
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