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However, if you experience severe reactions, you should stop using the medication and consult your healthcare provider immediately

Further, its effectiveness appears to gradually decrease after prolonged use of more than a year ( While phentermine has been shown to be effective for weight loss, it may work better when combined with topiramate

Dehydration is a known risk factor that can stress kidney function, making fluid intake critical when combining these compounds

Dehydration risk increases when appetite suppression combines with thyroid hypermetabolism, so prioritize hydration and electrolyte intake

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