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Description
The pattern makes biological sense
Now, early-stage research has begun to suggest that GLP-1 drugs like semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro) may reduce the risk of certain types of cancer and help prevent cancer from spreading after a diagnosis
In this context, incretin mimetics that bind GLP1R resulting in suppressed downstream signaling could instead be considered an antagonist rather than an agonist
Next Steps: This is currently a proposal
Gastrointest Liver Physiol
Routine monitoring of liver enzymes is not universally required for all patients initiating GLP-1 receptor agonist therapy, as these medications are not typically associated with drug-induced liver injury
