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Tirzepatide (Mounjaro, Zepbound) Tirzepatide is a dual GIP/GLP-1 agonist, meaning it acts on two receptors instead of one

Leach M et al

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Cardiovascular benefit for GLP-1RAs was shown in 2016 for liraglutide in the LEADER trial and semaglutide in the SUSTAIN 6 trial

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