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The CARPREG II risk prediction index assigns points based on a number of different predictors including prior cardiac events or arrhythmias, baseline New York Heart Association Class III-IV or cyanosis, presence of a mechanical valve, ventricular dysfunction, high risk left-sided valve disease or left ventricular outflow tract obstruction, pulmonary hypertension, and coronary artery disease or high-risk aortopathies

Intriguingly, GLP-1RAs are neuroprotective in animals and several trials have examined the actions of exenatide in people with Parkinsons disease (1)

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Ghrelin receptors mediate ghrelin-induced excitation of agouti-related protein/neuropeptide Y but not pro-opiomelanocortin neurons

This will vary between patients depending on their body type, any existing health concerns, and how their body reacts to the GLP-1 medication

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