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NICE recommends semaglutide (Wegovy) only through specialist tier 3/4 weight management services for adults with BMI 35 kg/m (or 32.5 kg/m for certain ethnic groups) plus at least one weight-related comorbidity, and only after intensive lifestyle intervention has been tried

Tirzepatide is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus and chronic weight management

The databases searched included PubMed, Embase, OVID, CINAHL, and Cochrane

If you have type 2 diabetes or obesity and are already considering a GLP-1 agent for metabolic reasons, then the potential brain benefits are a compelling additional advantage

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I would think happier employees and with a better quality of life would be more useful to the employer from a work efficiency standpoint as well. However, some people might do well with diet and exercise counselling and reducing the stigma surrounding obesity, potentially reducing the need for reliance on GLP-1 drugs
