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3 Results of reduced GIP receptor activation in humans Some GIP receptor antagonists have contributed to the elucidation of the physiological properties of endogenous GIP

( Epub 20221021 )

Most available evidence comes from animal models, small observational studies, and post-hoc analyses rather than dedicated randomized controlled trials

200,201 Additionally, incretin mimetic drugs targeting multiple receptors for greater efficacy, including glucagon and GIP receptors, are under development

31,32 Some patients display alterations in mental status

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