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Chronic Disease Prevalence : Rising global rates of type 2 diabetes and obesity are expanding the patient pool for GLP1 therapies, increasing demand for both glycemic and weight management indications

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Coskun T, Sloop KW, Loghin C et al (2018) LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: from discovery to clinical proof of concept

However, in patients with T2DM (69) and, although not to the same degree, in obese patients with normal glucose tolerance (70), the overall incretin effect is reduced

[DOI] [PMC free article] [PubMed] [Google Scholar] 113.Mullins R.J., Mustapic M., Chia C.W., Carlson O., Gulyani S., Tran J., Li Y., Mattson M.P., Resnick S., Egan J.M., et al