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An exploratory mediation analysis of the effects on kidney outcomes (composite of macroalbuminuria, decreased GFR, renal death) with liraglutide and semaglutide in patients with T2DM in the LEADER and SUSTAIN-6 trials observed that HbA1c mediated 2526% and SBP 922% of kidney effects with a negligible contribution of the other parameters studied, such as body weight [15]

Die verschiedenen Wirkstoffe variieren leicht in ihrer Struktur, sodass geringfgige Unterschiede in der Wirksamkeit und Wirkdauer entstehen

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