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However, statistical mediation analyses from trials such as SELECT suggest that only a portion of the MACE reduction is explained by weight loss alone, pointing to direct, weight-independent vascular and cardiac benefits [12,66]

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Consequently, the shape of GLP-1 demand may prove to be more important than the overall level of demand being another oral option in a category that until recently, has been dominated by injections

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Earlier this month, the FDA approved a new Eli Lilly drug, Zepbound (tirzepatide), for chronic weight management in adults who have at least one weight-related health condition

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