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This activation slows gastric emptying, keeping food in the stomach longer and creating prolonged feelings of fullness

These include reducing inflammation, diminishing tau phosphorylation, and improving synaptic function, in addition to their influence on insulin resistance [30]
Circ Res (2001) 89:44552

These therapies are also contraindicated during pregnancy due to potential effects on fetal development

Therefore, overall, the benefit of GLP-1RAs for heart failure has been difficult to confirm (Figure 1)
