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Precautions & Warnings Should not be used in patients with type 1 diabetes mellitus or for the treatment of diabetic ketoacidosis
Do them before you enroll, not after

Table 12: Study of Different Times of Once Daily Insulin Glargine Dosing in Type 1 (Study H) and Type 2 (Study I) Diabetes Mellitus Progression of Retinopathy Evaluation in adults with Diabetes Type 1 and Diabetes Type 2 Insulin glargine was compared to NPH insulin in a 5-year randomized clinical study that evaluated the progression of retinopathy as assessed with fundus photography using a grading protocol derived from the Early Treatment Diabetic Retinopathy Scale (ETDRS)

[7] [8] Supply is generally restricted to regulated clinical trial settings
GLP-1 receptor agonists slow gastric emptying, meaning food remains in the stomach longer than usual

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