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When generics do arrive, theyll typically launch around the same time across regions once patents expire and manufacturers can legally enter the market

doi: 10.1016/S2213-8587(22)00187-5

However, a condition called gastroparesis , severe slowing of stomach emptying, has been reported in a small number of patients, particularly those on long-term use

The review quantified weight regain after stopping weight management medications and estimated an average regain of about 0.9 pounds per month, with weight and cardiometabolic improvements projected to drift back toward baseline within roughly 1 to 2 years after stopping

Some supplements that get marketed as natural weight loss supplements for women specifically play on this (often with little evidence), while others do have real relevance

Effects have included severe nausea, severe vomiting, and severe hypoglycemia