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Researchers believe these benefits may come from improvements in cardiovascular health, reduced inflammation, better metabolic control, and improved liver health

doi: 10.1161/CIRCRESAHA.109.201590 120 GrabowskaWSikoraEBielak-ZmijewskaA

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Conversely, treatment of MDAMB231 cells with an OGT inhibitor OSMI1 led to a marked reduction in YAP OGlcNAcylation, diminished interaction with EIF3H as determined by both coimmunoprecipitation and PLA assay, and a decrease in YAP protein levels (Figure 3GI