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GLP-1 Patch delivers a science-backed, non-medicated solution to appetite control and weight management

Main results HbA1c, body weight, and FPG SGLT2i compared to placebo Four RCTs were included, with a total of 626 patients (304 in the SGLT2i group and 322 in the placebo group), which compared the changes in both HbA1c and body weight among patients with T2DM and low cardiovascular disease risk, from baseline to follow-up ( 2 = 0%) ( Figure 2A ) and body weight levels with low heterogeneity (MD: -1.32, 95% CI: -1.82, -0.82

2.2 Indications The currently approved indications for these agents include: Type 2 diabetes mellitus Overweight and obesity Beyond diabetes and obesity, further indications under investigation for GLP1 RAs include: Osteoarthritis Obstructive sleep apnea Metabolic dysfunction-associated steatotic liver disease Metabolic dysfunction-associated steatohepatitis 2.3 Benefits and Harms of Continuation/Discontinuation in the Perioperative Period: 2.3.1 Benefits: According to the guidelines, the acute use of these drugs may offer benefits based on published data: Improved perioperative glycemic control Lower postoperative insulin requirements Reduced risk of hypoglycemia These benefits may lead to reduced complications associated with hyperglycemia (such as a shorter hospital stay, fewer surgical site infections, less acute kidney injury, fewer acute coronary syndromes, reduced critical care admissions, and shorter durations on a ventilator) Improved cardiovascular outcomes 2.3.2 Harms There is an increased risk of pulmonary aspiration

All GLP-1 medications follow a gradual dose-escalation (titration) schedule to minimize side effects like nausea and allow your body to adjust

Cardiovasc Diabetol 20:205

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