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DALYs and mortality related to obesity are the consequence of multiple comorbidities such as cardiovascular (i.e., heart failure) and metabolic diseases (i.e

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The tradeoff: retatrutide appeared to show higher rates of nausea (42.4%), diarrhea (32.0%), and vomiting (25.3%) than tirzepatide or orforglipron at their top doses

Key players in Chiles GLP-1 segment: Novo Nordisk Market leader with Ozempic, Victoza, and Wegovy Eli Lilly Bringing innovation with Mounjaro (Tirzepatide) Sanofi Providing Soliqua, a GLP-1 + insulin combo CFR Pharmaceuticals (Abbott) Local affiliate with strong market access Biocon Expanding biosimilar reach in Latam AstraZeneca Strategic focus on metabolic & cardiovascular synergy With increasing physician adoption and patient demand, Chile is evolving into a high-opportunity market for obesity and type 2 diabetes therapies

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