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Studies have shown that it acts as a powerful antioxidant, combating cell damage caused by reactive molecules called free radicals

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These preclinical findings triggered regulatory caution: the FDA classifies semaglutide as Pregnancy Category C, meaning human safety data during lactation remains incomplete

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Constitutive hGPR17L activity inhibited GLP-1 secretion, and MDL29,951 treatment further inhibited this secretion, which was attenuated by treatment with the GPR17 antagonist HAMI3379

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