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First, if the solution has become contaminated with bacteria due to improper storage of a multi-dose vial, injection carries a risk of infection

Note: These dosing guidelines are from clinical trials only and not yet FDA approved

Accumulation of misfolded proteins in the ER triggers the unfolded protein response (UPR), in which C/EBP homologous protein (CHOP) is activated, subsequently activating the caspase family and inducing chondrocyte death 12

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A proper evaluation should include: Medical history review Lab testing (metabolic and hormonal markers) Discussion of expectations Avoid programs that skip clinical evaluation

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