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PIONEER 18 enrolled patients with early, established, and advanced T2D from a global population
Prosecution History Estoppel: Understanding What the Patent Owner Gave Away Every pharmaceutical patent has a prosecution history, the complete record of correspondence between the applicant and the patent examiner during the application process
One study found that participants lost over 24% of their starting weight after 48 weeks of treatment
This restriction exists because elderly patients often have decreased kidney function, which may increase the risk of lactic acidosis
Proper dosing is essential
Okay, don't just go to where you're uncomfortable
