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Retrieved 3 March 2023

For example, semaglutide 2.4 mg (Wegovy) yields approximately 15% body weight reduction in clinical trials, while lower doses used for diabetes (Ozempic) produce more modest weight loss
However, a small percentage of cases are familial, resulting from mutations in specific genes [82]
Unlike injectable formulations that typically require cold-chain storage, oral GLP-1RAs bypass refrigeration constraints, thereby reducing manufacturing and distribution costs and improving accessibility in resource-limited settings [73]
We conclude that semaglutide-induced reduction in obtaining rewards also affected cue and reward-related licking, but not latency, dopamine activity during reward collection and home cage chow intake
