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Liraglutide injection was initially approved for adults with type 2 diabetes in 2010, with an expanded indication in 2019 including children and adolescents aged 10 to 17 years

Stopping abruptly can lead to several challenges: 1

For example, FDA writes in the Kenil Healthcare Private Limited warning letter: On March 26, 2025, FDA held a teleconference with you and your U.S

The therapeutic benefits of these agentsglycaemic control, cardiovascular protection, and weight managementmust be balanced against largely theoretical aspiration risks

Significant weight loss can often be seen within 12-16 weeks, depending on individual factors like diet and exercise

As such, glomerular lesions occur which include glomerular basement membrane thickening, podocyte effacement and loss, mesangial expansion, epithelialmesenchymal transition EMT and fibrosis, collagen deposition, damage to the capillary architecture and an influx of inflammatory cells including macrophages