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Le professeur Serra a dvelopp une technique permettant de contourner ce problme et d'utiliser l'I.R.M

Some pharmacies also use unusual concentrations like 2.4 mg/mL or 3.33 mg/mL

Interestingly, a single amino acid modification to this tolerogenic epitope is sufficient to break tolerance and dramatically increase the immunogenicity of the peptide [9]

This diminishing-returns curve is what allows less frequent dosing to preserve most of the effect

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