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Some people also report that they have pain when swallowing, not just that its difficult to do so

The most common are gastrointestinal complaints : nausea, vomiting, diarrhoea, constipation

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Reference: In Silico Pharmacogenomic Assessment of Glucagon-like Peptide-1 (GLP1) Agonists and the Genetic Addiction Risk Score (GARS) Related Pathways: Implications for Suicidal Ideation and Substance Use Disorder by Alireza Sharafshah, Kai-Uwe Lewandrowski, Mark S

Activation of DMH LepR neurons has been shown to be sufficient to inhibit food intake [53]