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Lo sviluppo del test radioimmunologico dellinsulina ha consentito la descrizione dell effetto incretinico 7 , vale a dire che il glucosio somministrato nellintestino potenzia la secrezione di insulina in misura maggiore rispetto alla stimolazione isoglicemica della secrezione di insulina ottenuta attraverso la somministrazione endovena di glucosio

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