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Purpose This study aimed to develop a novel semaglutide-loaded dry powder inhaler (DPI) with improved bioavailability compared with oral administration while avoiding discomfort associated with injection

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Avoid repeated freeze-thaw cycles to maintain receptor binding affinity.Research Protocol Applications Glucose homeostasis and diabetes mechanism studies Weight management and appetite regulation research Cardiovascular protection and MACE prevention studies Neuroprotection and cognitive enhancement research Chronic kidney disease progression studies NAFLD/NASH mechanism investigations Anti-inflammatory pathway research Combination therapy optimization studies Clinical Translation PotentialGLP1-R research applications span from basic mechanism studies to translational research for multiple therapeutic areas

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