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Iraqi J Med Sci 2016

This approach is limited by the categorical nature of fibrosis staging, which may not fully reflect changes within stages or accurately predict clinical outcomes4, and improvements in fibrosis do not always correlate with immediate clinical outcomes, complicating the interpretation of trial results4

What they're saying: "It is statistically significant, and the consequences of hypotension can be terrible

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You are essentially recreating what the body does naturally in a pre-menopausal state: maintaining adequate estrogen signaling alongside robust GLP-1 activity

Neuroscience 170 (4): 1239-48