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Key Point to Remember: MS = Young women, CNS demyelination, relapsing-remitting neurological deficits, MRI plaques, CSF oligoclonal bands, treated with steroids + disease-modifying agents.

Mechanistic Insight: Tirzepatide appears to restore HPT-axis function and reactivate natural testosterone production, unlike exogenous testosterone, which suppresses it

Additionally, GLP-1 agonists improve metabolic functions by increasing the production of short-chain fatty acids like butyrate, propionate, and acetate, which serve as energy sources for colonocytes, modulate immune responses, and enhance the production of gut hormones that regulate appetite and glucose homeostasis
