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A: Retatrutide is a synthetic peptide currently being studied for its potential effects on metabolism and weight loss

121 However, PARP inhibition impedes DNA repair, increases DNA damage, and accelerates cancer initiation

While GLP-1s and similar peptides famously suppress appetite, reduce blood sugar, and cause weight loss, a growing body of research suggests they might also do much more: curb inflammation all over your body, increase mitochondria in skeletal muscle to give you more energy and help you build strength, and reduce the risk of conditions ranging from Alzheimers to heart disease to alcohol use disorder

Exenatide was the first drug in this class to be used in the treatment of type 2 diabetes

Common gastrointestinal side effects include nausea, vomiting, and diarrhoea, which may reduce fluid intake or increase fluid loss

Consensus report