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Although an increase in heart-rate per se is not a major problem for most people, it is salient in the case of GLP1R, GIPR or GR agonists since the target patient population of these agonist are obese patients, who likely already suffer from cardiovascular complications

The data showing cagrilintide preferentially reduces fat mass while preserving lean mass is compelling for researchers who care about body composition, not just the scale number

Basic and Clinical Neuroscience , 14 (3), 341354

Effect sizes were assessed sequentially up to and including the trial that reached the RIS

(2025, June 10)