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Indeed, these studies were originally designed primarily as safety studies, and the accumulation of a large number of CV events in high-risk patients was a strategy to limit the sample size and duration of these trials [37]
But "present in the system" and "detectable on a drug panel" are completely different things

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doi: 10.3920/BM2020.0111
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doi:10.1007/s00125-010-2028-x 263
