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PlexusDx's Precision Peptide Genetic Test can identify your genetic predispositions across 14 metabolic pathways, including markers like FTO rs9939609 and MC4R rs17782313, which influence how aggressively your body responds to GLP-1 therapy

Sci Rep 11:9167

A large study in the BMJ published in March of more than 600,000 US veterans with Type 2 diabetes found that starting a GLP-1 was associated with a 14% lower overall risk of developing alcohol, cannabis, cocaine, nicotine, and opioid use disorders

Tirzepatide demonstrates approximately 5-fold selectivity for GIP over GLP-1 receptors, making it a GIP-dominant dual agonist

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Also, the liraglutide-treated group experienced weight loss and mild to moderate gastrointestinal symptoms such as mainly nausea (14%), diarrhea and vomiting, while the insulin-therapy group gained weight