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Sustainable fat loss is a metabolic problem, not a medication problem

Furthermore, many patients struggle with side effects and adherence before seeing a clinically meaningful improvement

A 2020 study showed that those taking berberine lost on average about 2.07 kg (4.5 lbs) over roughly 1 to 3 months 18

Additionally, patients taking medications that cause weight gain (certain antipsychotics, antidepressants, or corticosteroids) may experience slower weight loss

Given these diseases high prevalence and diverse underlying mechanisms, the continued use of GLP-1RAs is supported

While prior gallbladder disease is not an absolute contraindication, it may influence the risk-benefit assessment